† NASHTest is a combination of age, gender, height, weight serum triglycerides, cholesterol, α2-macroglobulin, apolipoprotein A1, haptoglobin, γ ...
Here, we reveal the role of Ras-related protein Rab-2A (Rab2A) in mediating LD-Golgi interactions, thereby contributing to very-low-density lipoprotein (VLDL) lipidation and secretion in hepatocytes.
Importantly, the gene is linked to hepatocyte lipid accumulation and, by extension, to conditions like hepatic steatosis. Its loss-of-function mutation, rs72613567, results in a truncated ...
Chronic liver disease (CLD) is a growing global health challenge, accounting for millions of deaths each year. Its major ...
Steatotic liver disease is the overarching term for conditions characterised by abnormal lipid accumulation in the liver (liver or hepatic steatosis). Steatotic liver disease encompasses what was ...