This collection of Research and Review-type articles highlights the role of the IL-17 pathway in inflammatory diseases, and how our improved understanding of the mechanisms of disease has revealed ...

目前，多款自免领域的国产抗体药物已密集进入商业化阶段。IL-17是其中竞争最激烈的靶点之一，已在银屑病、支气管哮喘、慢性阻塞性肺病、类 ...

Research on the role that genes play in psoriasis has led to targeted therapies to reduce symptoms and slow disease ...

*仅供医学专业人士阅读参考众所周知，内分泌治疗是多数乳腺癌患者治疗中不可或缺的手段，雌激素受体（ER）则是内分泌治疗主要的打击目标之一。然而实话实说，别看内分泌治疗的使用都几十年了，但相关的机制层面研究还是在不断刷新着认知，比如随着乳腺癌逐步迈入免疫 ...

Belgian biopharma company UCB is bringing up the rear of the IL-17 inhibitor category with its bimekizumab drug, so is celebrating new late-stage data showing superiority to the class leader.

Let’s take a look at how differential signaling is different from single ended, and what that means for engineers and for users. Collectively, standards like TTL, CMOS, and LVTTL are known as ...

Then, IL-2 signaling is transduced through three distinct pathways: JAK-STAT, MAPK/ERK and PI3K/Akt/mTOR. Recent studies have identified that the IL-2/IL-2R signaling pathway is an essential ...

More information: Linying Li et al, CsPHRs-CsJAZ3 incorporates phosphate signaling and jasmonate pathway to regulate catechin biosynthesis in Camellia sinensis, Horticulture Research (2024).

BEIRUT — The Israeli military on Thursday warned people to evacuate a city and other communities in southern Lebanon that are north of a U.N.-declared buffer zone, signaling that it may widen a ...

This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...

Department of Immunology, Key Laboratory of Medical Molecular Virology (MOE, NHC, CAMS), School of Basic Medical Sciences, Department of Trauma-Emergency & Critical Care Medicine, Shanghai Fifth ...