CDC42 drives ciliary actin polymerization and ectocytosis. The hyperactivation of ciliary CDC42, along with excessive ...

Focal adhesion is a type of adhesive contact between the cell and extracellular matrix through the interaction of the transmembrane proteins integrins with their extracellular ligands, and ...

Join the Lab of Tim Springer Tim Springer, a leader in integrin biology, invites aspiring scientists to join his lab to advance groundbreaking research in integrin transmembrane signaling, TGF-β ...

The receptors and proteins were filtered from multiple datasets (Oncomine database) comparing prostate tumor tissue with normal tissue (based on Gene Ontology and statistical false-discovery rate ...

Integrin adhesion complexes (IACs) are integrin-based plasma-membrane-associated compartments where cells sense environmental cues. The physical mechanisms and molecular interactions that mediate ...

One section of the protein—called the β-propeller—sits on the outside surface of the membrane. The structure of the β-propeller is similar to a section of another protein—called α-integrin—that also ...