VEGF regulation is crucial, involving pathways like HIF1A/VEGF, VEGF-AKT/eNOS, and VEGF-induced activation of the p38MAPK signaling pathway, which facilitates blood vessel formation. The Wnt/β-catenin ...

If 2α is a transcription factor at the center of all this machinery or degradation of [von Hippel–Lindau (VHL)] at the center of renal cell cancer, and if 2α govern, you know, the activity of multiple ...

A study of more than 700 counties across multiple U.S. states found a link between childhood leukemia and levels of decaying radon gas, including those lower than the federal guideline for mitigation.

Leukemia is a type of blood cancer that begins in the bone marrow, where the blood cells are produced. People with leukemia have many abnormal white blood cells (leukocytes) in their blood.

People with Down syndrome face a higher risk of developing leukemia. Now researchers explain why, by identifying specific changes in blood cells of people with Down syndrome. People with Down ...

While most of the infections remain asymptomatic, roughly 5% lead to aggressive diseases like adult T-cell leukemia/lymphoma—a form of cancer with a prognosis of less than a year. "As a human ...

Some people don't have any symptoms. They are diagnosed because they have a routine blood test for something else. If you have any of these symptoms you must get them checked by your GP. But remember, ...

G6PD (glucose‐6‐phosphate‐dehydrogenase) is a key enzyme in the glycolytic pathway and has been implicated in the pathogenesis of cancer and pulmonary hypertension‐associated vascular remodeling. Here ...

Angiogenesis inhibitors that target vascular endothelial growth factor (VEGF) signalling pathways have proved successful for the clinical treatment of various types of cancer. However, a ...

The Consumer’s Guide to Anti-VEGF Treatments for Wet AMD Anti-VEGF treatments are the best available treatment for wet age-related macular degeneration (AMD). Learn how... The Consumer’s Guide ...