A plasmid DNA (pDNA) template is used as the ... template generation After aligning on a strategy for DNA production, a linearized DNA template is generated as the starting material for the ...

Nuclear condensates play many important roles in chromatin functions, but how cells regulate their nucleation and growth within the complex nuclear environment is not well understood. Here, we report ...

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).