Activation of the TH17 pathway leads to pro-inflammatory effects mediated by interleukin 17 with stimulation of osteoblast, macrophages, and fibroblasts with the consequences of secretion f ...

Interestingly, the presence of intraepithelial Th17 was significantly associated with patient survival ... IL-8 (all from BD Biosciences) or granulocyte-macrophage colony stimulating factor (GM-CSF) ...

CD131 was associated with endoscopic and pathological severity of ulcerative colitis as well as macrophage and T cell infiltration into the colon. (a) Gene expression dataset shows relative CSF2RB ...

Results The GCPM ecosystem coordinates a unique immunosuppressive pattern distinct from that of primary GC, which is dominated by a stroma-myeloid niche composed of SPP1+tumour-associated macrophages ...

From tumor necrosis factor alpha (TNF-α), to IL-17 inhibitors, and then to IL-23 inhibitors, biologics have brought new light ...

This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...