SARS-CoV-2 spike-specific nasal-resident CD49a + CD8 + memory T cells exert immediate effector functions with enhanced IFN-γ production For infections that affect peripheral tissues it is better ...

Discovered 30 years ago, microRNAs are increasingly recognized as important regulators of cell physiology and human disease.

Discover research by Hongbo Chi, PhD, that uncovers the interplay between organelles, nutrient-dependent signaling pathways ...

When it comes to getting a cold or the flu, there is a commonly held belief that men take it harder than women, exaggerating ...

"NIH selects Emergex’s T cell vaccine for trials under Project NextGen" was originally created and published by Clinical ...

The ability to therapeutically manipulate the immune system presents a multitude of potential opportunities for treating ...

Metabolic factors influence tissue immunity in an intricate interplay between nutrient availability, organelle biology and tissue-resident memory T (TRM) cell development.

Once acquired infection persists for life requiring continuous life long cellular immunity (CD8 memory T cell and IFNγ dependent) for host survival. Development of this response relies on both ...

This ongoing phase I/II clinical trial is designed to treat patients at high risk of post-transplant relapse. The generated therapeutic T cells are enriched for the subset of highly persistent ...

Those studies show that infection-fighting immune cells, known at CD8+ T cells, persist at the site of healed sores and accumulate near sensory nerve endings, where reactivating viruses are released.

Just like occasional lapses in memory, these issues can also be attributed to other age- or health-related changes (or just a bad day), so experts emphasized that they aren’t necessarily red ...