Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

1Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang-si, Republic of Korea. 2Immuno-Oncology Branch, Graduate School of Cancer Science ...

University of Washington-led research, published in 2023, discovered microglia in the brains of people with Alzheimer's disease were in a pre-inflammatory state more frequently, making them less ...

Understanding the intricacies of the brain tumor microenvironment (TME) is crucial for developing precise diagnostic and therapeutic strategies, but the high degree of complexity often limits research ...

Mosquito-borne alphaviruses are important causes of epidemic encephalomyelitis. The immune response plays an important role in disease; however, immune-mediated mechanisms of pathogenesis and ...

Microglia exhibit both maladaptive and adaptive roles in the pathogenesis of neurodegenerative ... #MCA1957), anti-human CD68 (1:100, R&D, #MAB20401), anti-mouse Cd45 (1:100, Bio-Rad, #MCA1388), ...

The identification of “disease-associated microglia” (DAM) follows suit in this broader understanding of phenotypic ... characterized by the progressive degeneration of upper and lower motor neurons.

The state of the underlying myelin content of the tissue was also characterized. The imaging approach could distinguish between the immune cells of the brain (known as resident microglia) and a type ...