In this study, we identified the anatomical patterns of cardiac ... mice at E10.5. After 3 days, we harvested the embryos and observed that all the embryos with ablated fibroblasts (Pdgfra-CreER+/-; ...

The fatty acid transport/oxidation gene FABP4 acts as a metabolic and inflammation regulator, whose inhibition can attenuate kidney and renal interstitial fibrosis. However, its role in the heart ...

Introduction: Cardiac fibrosis is a typical pathophysiological process associated with ECM deposition, resulting in tissue scaring and organ dysfunction. No specific antifibrotic therapies exist for ...

The team used these newly generated stem cells to help form a living, breathing mouse from a developing embryo, according to published findings in Nature Communications. The discovery was ...

Keywords: Inflammation, Fibrosis, Chronic Inflammatory Diseases, Tissue Remodeling, Molecular Pathways, Immune Cells, Macrophages, T Cells, Fibroblasts, Signal Transduction, TGF-β, NF-κB, JAK/STAT, ...

Human embryonic stem cells are obtained from embryos ... does not contain all the biochemical factors that promote specific cardiac myocyte differentiation, transplantation of pluripotent hESCs ...

The following is a summary of “Role of fibrosis in endometriosis: a systematic review,” published in the July 2024 issue of Obstetrics & Gynecology by Vissers et al. Fibrosis is a key pathological ...