The novel co-occurrence of JAK2, CALR & MPL mutations in a patient with myelofibrosis challenges previous knowledge that ...
When a JAK2 mutation occurs, this genetic change can lead to various health issues. Hematopoietic stem cells are located in the bone marrow (the spongy tissue inside the bones) and have the ...
MPNs have been linked to random somatic mutations in certain genes including in a gene called JAK2. However, mutated JAK2 is commonly found in the global population, and the vast majority of these ...