Despite disappointing results in the genetic neurodegenerative disorder, the drug shows potential for treating obesity.

Jakarta, - Unlocking the Potential of Peptides in Muscle Cell and Bone Science Peptides, tiny chains of amino acids linked by ...

Mutational signature analyses of de novo mutations in multi-child human families suggest that inaccurate DNA mismatch repair, DNA damage, and replication errors are major sources of age-related ...

Different genes control different traits and these can be both positive and / or negative, depending on how the breeding of the animal is managed. Myostatin is a term being mentioned more often in ...

Data support that Scholar Rock’s unique approach to selective myostatin inhibition could improve body composition in people living with obesity and on an existing background treatment - Scholar Rock’s ...

The impact of negative selection against deleterious mutations in endangered species remains underexplored. Recent studies have measured mutation load by comparing the accumulation of deleterious ...

1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. 2Breast Tumor ...

When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing cancer. There are many types of EGFR mutations. The EGFR protein lives in the cell membrane with ...

Oncogenic mutations often involve single nucleotide substitutions at specific hotspots, leading to hyperactive or gain-of-function variants. Tumor suppressor mutations typically involve indels ...

Ibio Inc. has announced progress under its collaboration with Astralbio Inc. on a joint myostatin program for cardiometabolic disease and obesity. Ibio leveraged its technology to rapidly advance the ...

This study highlights how the deletion of the MSTN gene in pigs affects the gut microbiota and leads to changes in skeletal muscle growth and function. By transplanting the remodeled gut microbiota ...