We propose that this force-dependent regulation of nucleotide exchange is the basic mechanism of gating behaviour — a key regulation for the efficient hand-over-hand movement. The regulatory ...

Despite this knowledge, the precise mechanism underlying the formation of these nascent membrane structures remains poorly understood. To gain insights into this process, researchers at the ...

A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy.

1998). The proton buffering model may coexist with the FA protonophore model and the biphasic proton transport mechanism. In Figure 3, we used in silico prediction modeling to determine the potential ...

Jaeseung Youn, has successfully replicated the structure of wrinkles in biological tissue in vitro, shedding light on the mechanisms driving their formation. Their findings were published in the ...

It is because niclosamide, Xafty's main pharmaceutical ingredient, is anticipated to provide practical therapeutic effects to ...