In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

Estrogen plays an important role in bone biology ... osteocytes (a final differentiated cell type of the osteoblast lineage), and bone marrow stromal cells, ESR2 is less important in mediating ...

Bone marrow is the soft, fatty tissue inside large bones like the hip and thigh bones. It develops the body's red blood cells that carry oxygen, white blood cells that fight infections, and platelets ...

The bone marrow, a vital part of our body, greatly affects our overall health. Located within our bones, this soft, fatty tissue is involved in producing red and white blood cells, platelets ...

Oct. 11, 2024 — Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation ...

X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

Nov. 6, 2024 — Children whose mothers took extra vitamin D during pregnancy continue to have stronger bones at age seven, according to ... Two Key Genes Identified Linking Rheumatoid Arthritis ...

Objective To compare the effects of interleukin-6 (IL-6) receptor and tumour necrosis factor inhibition on inducing repair of existing bone erosions in patients with very early rheumatoid arthritis ...