Researchers at LMU University Hospital have discovered a new molecular switch that protects against cell death.

Bacteria that cause diseases, so-called pathogens, develop various strategies to exploit human cells as hosts to their own ...

Mechanistically, ADCY7 translocates into the nucleus and serves as a transcriptional cofactor for CEBPA, binding to the promoter of CCL5 to promote its transcription, thereby facilitating CD8 + T cell ...

Therefore, almost all types of cells have polarity. In the intestine, cell polarity plays an important role in functions such as digestion and absorption of nutrients These functions as well as ...

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein ...

Researchers meticulously examined the gametogenesis of budding yeast, a process involving meiosis and spore formation, using live imaging techniques. Their findings revealed that during sporulation, ...

"GSDMD NTD inserts into the plasma membrane, i.e. the outermost membrane of the cell, as we already suspected, but not initially into the mitochondria, as postulated elsewhere," says Prof.

"GSDMD NTD inserts into the plasma membrane, i.e., the outermost membrane of the cell, as we already suspected, but not initially into the mitochondria, as postulated elsewhere," says Prof.

Delivery to the sides of the cell is well understood ... that most of their bulk resides within or outside of the plasma membrane and not inside the cell—de Caestecker hypothesized that proteins ...

A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future ...