ZyVersa Therapeutics (ZVSA) announces newly published data demonstrating that stroke-related cardiovascular injury and dysfunction is induced by AIM2 inflammasome activation and pyroptosis in ...
NLRP3 inflammasome activation, pro-inflammatory cytokine production and pyroptosis are key features of inflammation that contribute to liver fibrosis progression, cirrhosis and end-stage liver failure ...
The team showed that MCC950 prevented the assembly of the NLRP3 inflammasome in mouse cells exposed to a bacterial toxin and blocked IL-1β secretion and cell death by pyroptosis. In mice ...
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