A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that ...

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new ...

Altered RNA processing is highly damaging to neurons, adding a new toxic component to the evolution of AD. Currently, the ...

They can also be within the exon.” RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence ...

Defects in RNA splicing or mutations can lead to a wide variety of diseases, ranging from metabolic disorders to cancer. A point mutation occurs when a single nucleotide is erroneously inserted ...

This reaction takes place in the spliceosome, which is formed by several snRNP subunits termed uridine-rich small ribonucleoproteins (UsnRNP), and numerous non-snRNP splicing factors. The spliceosome ...