Ezutromid was designed to treat DMD by boosting utrophin levels to compensate for the faulty dystrophin protein that is the root cause of the very rare muscle-wasting disease. Summit reported ...

For example, it was recently shown that HEREGULIN can upregulate utrophin in mice carrying a mutation in dystrophin. [57] In this model, heregulin treatment was effective in improving muscle mass.

For innovation in medicinal chemistry leading to the identification of first in class utrophin modulators for the treatment of Duchenne muscular dystrophy. Throughout this endeavour has been, and ...

The muscular dystrophies are commonly associated with cardiovascular complications, including cardiomyopathy and cardiac arrhythmias. These complications are caused by intrinsic defects in ...

a medal and a certificate The winner will complete a UK lecture tour The winner will be chosen by the RSC Chemistry Biology Interface Prize Committee For innovation in medicinal chemistry leading to ...