Indeed, like CDK1, CDK5 is also a canonical cell-division-cycle CDK. We have established the role of CDK5 in cell division in non-cancer cells, but the CDK5–cyclin B1 complex might have an even ...

Recent work has discovered the role of the cyclin-dependent kinase (CDK)-binding protein Cks1 in degrading the CDK inhibitor p27 Kip1. This process is essential for DNA replication and is ...

Researchers have developed an innovative approach to treat cancers driven by kinase mutations, specifically targeting B cell ...