EGF receptor (EGFR) tyrosine kinase inhibitors (TKIs), given their low molecular weight, may be able to reach a higher concentration in brain tissues. Various reports and small studies ...

The FDA has granted Breakthrough Therapy designation to sacituzumab tirumotecan for patients with advanced or metastatic ...

CURE® spoke with a lung cancer treatment expert about study findings showing survival benefits with the addition of ...

Voronoi Inc. has discovered EGFR (Leu858Arg/Thr790Met/Cys797Ser triple mutant) and EGFR (del19/Thr790Met/Cys797Ser triple mutant) inhibitors.

colorectal (colon) cancer; epidermal growth factor receptor (EGFR); RAS; liquid biopsy; rechallenge; cetuximab; RAS; ...

Skin biopsies from EGFR inhibitor-treated and cicatricial alopecia patients revealed an active JAK-STAT1 signaling signature along with upregulation of antigen presentation and downregulation of key ...

Using FDA-approved EGFR inhibitors, such as vandetanib and dacomitinib, the team confirmed significant antiviral effects. Notably, vandetanib was highly effective, reducing viral RNA levels in ...

China’s drug regulator approved Alpha Biopharma Ltd.’s EGFR tyrosine kinase inhibitor (TKI), Zorifer (zorifertinib hydrochloride tablets; AZD-3759), as a first-line treatment for EGFR-mutated ...

Merck & Co., Inc. (MRK) announced Tuesday that the U.S. Food and Drug Administration has granted Breakthrough Therapy designation to ...