在一项新的研究中,来自德克萨斯大学西南医学中心的研究人员发现tRNA 可以决定 ...
撰文丨王聪编辑丨王多鱼排版丨水成文众所周知,根据中心法则,DNA转录为mRNA,mRNA再翻译为蛋白质,mRNA的降解速率是每个基因产生的蛋白质的数量的主要决定因素,而这又会影响细胞功能。例如,对于mRNA疫苗,mRNA存在更长时间会产生更多蛋白质,从而更好地激活免疫系统以抵抗感染;而对于CRISPR-Cas9基因编辑,产生Cas9蛋白 ...
科学家发现,转运 RNA (tRNA) 能够决定信使 RNA(mRNA)在细胞中的寿命,导致某些 mRNA 被稳定保存并翻译成更多的蛋白质,而另一些 mRNA 则被降解,从而限制蛋白质的生成量。
Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized ...
Fred Hutch researcher wins a $1M grant for a London-Seattle collaboration to find new therapies for drug-resistant prostate ...
Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA -- that molecular blueprint for life -- ...
Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...
Herpes simplex virus (HSV), the viral agent causing human genital herpes, recurs easily and poses significant harm to patients, while also being associated with atherosc ...
Director Elena Conti and her team at the Max Planck Institute of Biochemistry in Martinsried near Munich have now been able to show that the various molecular machines that translate and degrade mRNA ...
SINGAPORE - A cutting-edge mRNA production laboratory that can quickly produce materials for pre-clinical or animal studies for vaccines to respond to future pandemics, or drugs to combat cancers ...