Researchers from Ludwig Maximilian University of Munich presented a study in Nano Letters on the molecular organization of ...

Potent siRNAs against B4GALT1 were designed in silico and screened in vitro (Huh7 cells, primary mouse, human hepatocytes) as well as in vivo (C57BL/6 mice) for the selection of a lead Galomic siRNA.

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

At the American Heart Association’s Scientific Sessions, E-Therapeutics plc presented preclinical data for ETX-258, a Galomic siRNA being developed for the treatment of heart failure.

Compared to linear mRNA, circular RNAs offer greater stability during storage and delivery, along with more sustained effects due to their circular structure. This Review provides an overview of ...

Cross-species host–pathogen or mutualistic RNA communication, especially through extracellular vesicles, can have important applications, including gene silencing in agriculture and RNA-based ...

Ottawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada Department of Biochemistry Microbiology and Immunology, Faculty of Medicine, University of ...

Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable ...

Adhesion junction is crucial for the stability of the epithelial lateral membrane and the maintenance of cell polarity. E-cadherin is an essential cell-cell adhesion protein, with the canonical E ...