Cyclin-dependent kinase - Wikipedia
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression, ensuring the integrity and functionality of cellular machinery.
Cyclin-dependent kinases | Genome Biology | Full Text - BioMed …
2014年6月30日 · Wohlbold L, Larochelle S, Liao JC, Livshits G, Singer J, Shokat KM, Fisher RP: The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity.
Cyclin-dependent kinase complex - Wikipedia
A cyclin-dependent kinase complex (CDKC, cyclin-CDK) is a protein complex formed by the association of an inactive catalytic subunit of a protein kinase, cyclin-dependent kinase (CDK), with a regulatory subunit, cyclin. [1]
CDK | Learn Science at Scitable - Nature
Coordinated protein phosphorylation reactions control progression through the cell cycle. Learn how specific complexes of cyclins and cyclin-dependent kinases (CDKs) catalyze these reactions.
What are Cyclin-Dependent Kinases? - News-Medical.net
2023年8月24日 · Cyclin-dependent kinases are a type of serine/threonine kinase which are activated by cyclins to drive the progress of the cell cycle.
Cyclins and Cyclin-dependent Kinases | SpringerLink
Cyclins are known to function as the regulatory subunit of heterodimeric protein kinase complexes that also contain a catalytic subunit with serine/threonine kinase activity, known as cyclin-dependent kinase (Cdk).
The Cyclin-dependent kinase 1, as a serine/threonine protein kinase, is more than a cell cycle regulator as it was originally identified. During the last decade, it has been shown to carry...
Cyclin-Dependent Kinases (CDK) and Their Role in Diseases
2021年3月13日 · In dividing cells, cyclin-dependent kinase 2 (CDK2) is a major cell cycle component that controls the G1/S and S/G2 transitions. CDK2/CycE must phosphorylate Rb to induce S phase entry (mouse embryonic fibroblasts–MEFs) .
Cyclin-dependent kinases and rare developmental disorders
2020年8月6日 · Cyclin-dependent kinases (CDKs) form a family of 20 serine/threonine protein kinases that exert pivotal functions in fundamental cellular and molecular processes, such as cell division, migration, senescence, death, gene transcription, mRNA splicing, metabolism, and other important mechanisms (reviewed in [1, 2]. As indicated by their name and ...
Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activ - ity requires association with specific cyclin sub...
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