Catenin beta-1 - Wikipedia
Catenin beta-1, also known as β-catenin (beta -catenin), is a protein that in humans is encoded by the CTNNB1 gene. β-Catenin is a dual function protein, involved in regulation and coordination …
Wnt/β-catenin signalling: function, biological mechanisms, and ...
2022年1月3日 · In this article, we comprehensively review the Wnt/β-catenin pathway from the above five aspects in combination with the latest research. Finally, we propose challenges and …
The regulation of β-catenin activity and function in cancer ...
The activity of β-catenin is under the control of several highly regulated processes, including ligand–receptor interactions, β-catenin stability, β-catenin nuclear translocation and β-catenin …
Wnt/β-catenin signaling: components, mechanisms, and diseases
We discuss Wnt ligands, agonists and antagonists and their interactions with Wnt receptors. We also dissect critical events that regulate β-catenin stability from Wnt receptors to the …
The many faces and functions of β-catenin - PMC - PubMed …
β-Catenin (Armadillo in Drosophila) is a multitasking and evolutionary conserved molecule that in metazoans exerts a crucial role in a multitude of developmental and homeostatic processes. …
Wnt/β-Catenin Signaling: Components, Mechanisms, and …
We discuss Wnt ligands, agonists, and antagonists, and their interactions with Wnt receptors. We also dissect critical events that regulate β-catenin stability, from Wnt receptors to the …
The β-catenin/YAP signaling axis is a key regulator of melanoma ...
2019年12月24日 · Using coimmunoprecipitation and proximity ligation assays, we identified Yes-associated protein (YAP) as an important β-catenin-interacting partner in stromal fibroblasts. …
Wnt/β-catenin signaling components and mechanisms in bone
2024年7月10日 · In this review, we provide an update of Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and diseases. The Wnt proteins, receptors, …
A Simple Method to Assess Abundance of the β-Catenin Signaling …
β-catenin (CTNNB1) is a dual-function cell–cell adhesion/transcriptional co-activator protein and an essential transducer of canonical Wnt signals.
Wnt/β-catenin signalling: function, biological mechanisms, and ...
The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin signalling often …