Ceramide - Wikipedia
Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid joined by an amide bond. Ceramides are found in high concentrations within the cell …
The many faces (and phases) of ceramide and sphingomyelin I – single lipids
Ceramides, the simplest kind of two-chained sphingolipids, contain a single hydroxyl group in position 1 of the sphingoid base. Sphingomyelins further contain a phosphocholine group at …
Ceramides - LIPID MAPS
The stratum corneum contains high levels of ceramides (as much as 50% of the total lipids), including O-acylceramides, which exist both in the free form and linked by ester bonds to …
Plasma Ceramides Pathophysiology, Measurements, Challenges, …
2024年10月21日 · Ceramides are a family of lipid molecules, composed of sphingosine and a fatty acid, and transported by lipoproteins (primarily by low-density lipoproteins) in the …
The role of ceramides in metabolic disorders: when size and ...
2020年2月14日 · Here, we examine the emerging concept of how the intracellular localization of ceramides with distinct acyl chain lengths can regulate glucose metabolism, thus emphasizing …
Advances in determining signaling mechanisms of ceramide and …
Ceramide is a critical bioactive lipid involved in diverse cellular processes. It has been proposed to regulate cellular processes by influencing membrane properties and by directly interacting with …
Ceramides and other sphingolipids as drivers of cardiovascular ... - Nature
2021年3月26日 · The metabolism of lipids accumulated in blood vessel walls and the heart produces sphingolipids, such as ceramides, which are associated with the development of …
Unravelling neuronal and glial differences in ceramide …
2 天之前 · Ceramides are lipids that play vital roles in complex lipid synthesis, membrane function, and cell signaling. Disrupted ceramide homeostasis is implicated in cell-death and several …
Ceramides in Skin Health and Disease: An Update
While being a minor constituent of cellular membranes, ceramides are the major lipid component (along with cholesterol, free fatty acid, and other minor components) of the intercellular spaces …
Ceramide Metabolism in Cardiovascular Disease: A Network With …
2022年8月25日 · Growing evidence suggests that ceramides play an important role in the development of atherosclerotic and valvular heart disease. Ceramides are biologically active …