Co Crystallization - an overview | ScienceDirect Topics
Co-crystallization is defined as the process of crystallizing two components together in the same lamellar crystals, requiring similar chemistry in their repeat units and lattice parameters. It is a rare phenomenon in polymer blends where both components exhibit melt miscibility.
Chapter 1: Co-crystals: Introduction and Scope - Royal Society of …
2018年7月13日 · In this chapter, we will provide a brief overview of the history behind the nomenclature of co-crystals, as well as highlight some practical and versatile supramolecular design strategies based on site-specific strong intermolecular interactions for the directed assembly of co-crystals of considerable complexity.
Pharmaceutical co-crystals: A green way to enhance drug stability …
2023年11月2日 · This review offers a thorough investigation into pharmaceutical co-crystals, covering design, synthesis, characterization, and evaluation (Table 1). It explores diverse co-crystal formation methods, such as co-grinding, solvent …
Creating Cocrystals: A Review of Pharmaceutical Cocrystal …
2018年8月10日 · The Cocrystallization with Supercritical Solvent (CSS) technique uses the solvent power of supercritical CO 2 to suspend the API and the coformer as a slurry in liquid or supercritical CO 2, avoiding the use of toxic organic solvents.
Co-crystallization and small molecule crystal form diversity: …
Co-crystallization is the supramolecular phenomenon of aggregation of two or more different chemical entities in a crystalline lattice through non-covalent interactions. It encompasses the study of the manifestation of multi-component crystalline solids as well as their design.
Pharmaceutical cocrystals: A review of preparations, …
2021年8月1日 · Cocrystallization of a drug substance with a coformer is a promising and emerging approach to improve the performance of pharmaceuticals, such as solubility, dissolution profile, pharmacokinetics and stability.
Co-crystallization of atomically precise metal nanoparticles
2018年8月22日 · This paper reports co-crystallization of two atomically precise, different-size ligand-stabilized nanoclusters, a spherical (AuAg) 267 (SR) 80 and a smaller trigonal-prismatic (AuAg) 45 (SR)...
Co-crystals: Preparation, Characterization and Applications
2018年7月13日 · This book combines co-crystal applications of commercial and practical interest from diverse fields in to a single volume. It also examines effective structural design of co-crystals, and provides insights into practical synthesis and characterization techniques.
Co-crystallization as a Versatile Tool in Separations Technology
2018年7月13日 · Co-crystallization has been used for improving the physical and chemical properties of crystalline materials, especially of compounds that are not prone to salt formation. This chapter highlights recent developments in co-crystallization as an effective separation technique for the isolation/separation of APIs and chiral compounds.
Cocrystallization: A tool to modulate physicochemical and …
2021年4月1日 · cocrystallization is addressed as a powerful tool to modulate the properties of food-relevant polyphenols. As the first review concerning food related cocrystals, this review emphasizes cocrystals from food-grade coformers, summarizing production routes, solvents used, and safety-related problems. Key findings and conclusions.
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