Dendritic cell - Wikipedia
A dendritic cell (DC) is an antigen-presenting cell (also known as an accessory cell) of the mammalian immune system. A DC's main function is to process antigen material and present it on the cell surface to the T cells of the immune system. They act as messengers between the innate and adaptive immune systems. [ 1 ]
Dendritic Cell Overview | Thermo Fisher Scientific - US
Dendritic cells (DCs) play a pivotal role in the innate detection of pathogens and the subsequent activation of the adaptive immune response. DCs initiate the adaptive response by presenting antigenic peptides on major histocompatibility complex (MHC) molecules to induce T cell activation and differentiation.
Dendritic cell migration in inflammation and immunity
2021年7月23日 · Dendritic cells (DCs) play crucial roles not only in initiating protective immunity against invading pathogens but also in inducing immune tolerance toward harmless antigens. The...
Dendritic cells as orchestrators of anticancer immunity and ...
2024年2月7日 · Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells that regulate adaptive immunity, including against cancer. Therefore, understanding the precise...
Dendritic cells in cancer immunology and immunotherapy
2019年8月29日 · Dendritic cells (DCs) are a diverse group of specialized antigen-presenting cells with key roles in the initiation and regulation of innate and adaptive immune responses. As such, there is...
Human dendritic cell subsets: an update - PMC - National Center …
2018年2月27日 · Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid haematopoiesis that form an essential interface between the innate sensing of pathogens and the activation of adaptive immunity.
What are Dendritic Cells? - News-Medical.net
2022年9月5日 · Dendritic cells (DC) are a type of antigen-presenting cell (APC) that play an essential role in the adaptive immune system. The primary function of DCs is to present antigens and the cells are...
Dendritic cell biology and its role in tumor immunotherapy
2020年8月3日 · Our comprehensive review of DC biology and its role in tumor immunotherapy aids in the understanding of DCs as the mentors of T cells and as novel tumor immunotherapy cells with immense potential. As crucial antigen presenting cells, dendritic cells (DCs) play a vital role in tumor immunotherapy.
ISOLATION AND GENERATION OF HUMAN DENDRITIC CELLS
The ability to generate dendritic cells from monocytes provides a new and simple method for generating functionally mature dendritic cells from a population of cells that are relatively easy to isolate to homogeneity, as opposed to CD34 + stem cells or other precursor cells.
Dendritic cell subsets and locations - PubMed
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the foundation for DC biology, and the advances in the field identified different versions of DCs with unique properties and fun ….