Dopamine transporter - Wikipedia
The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded for in humans by the SLC6A3 gene (also known as DAT1), that pumps …
SLC6A3 Gene - GeneCards | SC6A3 Protein | SC6A3 Antibody
2024年10月2日 · Dopamine transporters (DAT) are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) widely distributed throughout the brain in areas of …
Dynamic control of the dopamine transporter in …
2021年3月5日 · In this review we summarize mechanisms governing DAT trafficking under normal physiological conditions and discuss how PD-linked mutations may disturb DAT homeostasis. …
SLC6A3 gene - MedlinePlus
The SLC6A3 gene provides instructions for making a protein called the dopamine transporter or DAT. This protein is embedded in the membrane of certain nerve cells (neurons) in the brain, …
Dopamine Transporter - an overview | ScienceDirect Topics
Human dopamine transporter gene. The DAT gene coding sequence is derived from 15 exons distributed across a >64 kb gene in humans. Whereas the human DAT coding region is of …
Overview of the structure and function of the dopamine …
SLC6A3 is the dopamine transporter (DAT) involved in the release and reuptake of dopamine from the synapse and extrasynaptic space into neurons and is integral to dopaminergic …
6531 - Gene ResultSLC6A3 solute carrier family 6 member 3
Epigenetic regulation of DAT gene promoter modulates the risk of externalizing and internalizing behaviors on a normative population: An explorative study. SLC6A3 as a potential circulating …
13162 - Gene ResultSlc6a3 solute carrier family 6 …
2024年8月7日 · DAT knockdown in the nucleus accumbens, but not in the caudate putamen, improve anxiety- and depression-like symptoms in adult mice and the data illustrate the …
SOLUTE CARRIER FAMILY 6 (NEUROTRANSMITTER TRANSPORTER, DOPAMINE …
The dopamine transporter (DAT), which is encoded by the SLC6A3 gene, mediates the active reuptake of dopamine from the synapse and is a principal regulator of dopaminergic …
The dopamine transporter gene SLC6A3: multidisease risks
2021年10月14日 · The human dopamine transporter gene SLC6A3 has been consistently implicated in several neuropsychiatric diseases but the disease mechanism remains elusive.