Overview of feminizing hormone therapy | Gender Affirming …
2016年6月17日 · A prospective study of transgender women taking 4mg/day divided dose oral estradiol or 100mcg transdermal estradiol, plus 100-200mg/day divided dose spironolactone found that all women achieved physiologic estradiol levels, though only 2/3 of the women achieved female range testosterone levels.[22]
Practical Guidelines for Transgender Hormone Treatment
A practical target for hormone therapy for transgender women (MTF) is to decrease testosterone levels to the normal female range (30–100 ng/dl) without supra- physiological levels of estradiol (<200 pg/ml) by administering an antiandrogen and estrogen.
1 Testosterone Cypionate/Enanthate and Estradiol Valerate/Cypionate are FDA approved for delivery only through intramuscular injections. However, for many patients, subcutaneous injection serves as a safe and effective alternative option due to decreased pain with
Feminizing hormone therapy - Mayo Clinic
2024年7月12日 · Another choice for feminizing hormone therapy is to take gonadotropin-releasing hormone (Gn-RH) analogs. They lower the amount of testosterone that the body makes and might allow you to take lower doses of estrogen without taking spironolactone. The disadvantage is that Gn-RH analogs usually are more expensive.
Transgender women: Evaluation and management - UpToDate
2023年10月12日 · Transgender women receiving hormone therapy should be monitored to avoid supraphysiologic serum estradiol (E2) concentrations (eg, maintain E2 levels <200 pg/mL [734 pmol/L]) and to verify that serum testosterone levels reach the physiologic female range .
The Use of Injectable Estradiol in Transgender and Gender …
Our scoping review suggests that guideline recommended doses of 2 to 10 mg/weekly or 5 to 30 mg/2 wk of estradiol cypionate or valerate for feminizing therapy in transgender and gender diverse adults often lead to supraphysiologic estradiol levels.
Hormone therapy for transgender patients - PMC - National …
2016年9月4日 · As a result, there are strong recommendations against the use of ethinyl estradiol in transgender patients . Oral (Estrace ®, Gynodiol ®) and transdermal (Alora ®, Climera ®, Esclim ®, Estraderm ®, Vivelle ®) estradiol and parenteral estradiol valerate (Delestrogen ®) are currently the
Information on Estrogen Hormone Therapy
Feminizing hormone therapy may include three different kinds of medicines: Estrogen, testosterone blockers, and progesterones. Estrogen. Estrogen is the primary “female” hormone. It is involved in many of the physical and emotional changes seen in transition.
rapy. AMAB = assigned male at birth. AFAB = assigned female at birth. T = testosterone. E = estradiol. 1 In many countries gender incongruence is considered sufficient for initiation of GAHT, rather than a diagnosis of gender dysphoria. 2Birth control options that won’t interfere with masculinization for AFAB people include progesterone-b...
Injectable estradiol preparations are recommended by the World Professional Association for Transgender Health Standards of Care 8 and the Endocrine Society guidelines. Many patients prefer this route of administration, but few studies have …
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