Exon junction complex - Wikipedia
An exon junction complex (EJC) is a protein complex which forms on a pre-messenger RNA strand at the junction of two exons which have been joined together during RNA splicing. The …
Comprehensive mapping of exon junction complex binding sites …
2023年11月7日 · The exon junction complex (EJC) is involved in most steps of the mRNA life cycle, ranging from splicing to nonsense-mediated mRNA decay (NMD). It is assembled by the …
A Day in the Life of the Exon Junction Complex - MDPI
2020年5月1日 · The exon junction complex (EJC) is a multi-protein complex and universal component of spliced messenger ribonucleoproteins (mRNPs) in metazoans that carries out …
Abstract | The exon junction complex (EJC) is deposited onto mRNAs following splicing and adopts a unique structure, which can both stably bind to mRNAs and function as an anchor for …
Diverse Roles of the Exon Junction Complex Factors in the Cell
2022年9月8日 · The exon junction complex (EJC) plays a crucial role in regulating gene expression at the levels of alternative splicing, translation, mRNA localization, and nonsense …
Transcriptome-wide modulation of splicing by the exon junction complex ...
2014年12月5日 · The exon junction complex (EJC) is a dynamic multi-protein complex deposited onto nuclear spliced mRNAs upstream of exon-exon junctions. The four core proteins, eIF4A3, …
The Exon Junction Complex Controls the Efficient and Faithful …
2016年8月2日 · The exon junction complex (EJC) that is deposited onto spliced mRNAs upstream of exon–exon junctions plays important roles in multiple post-splicing gene expression events, …
The Hierarchy of Exon-Junction Complex Assembly by the ... - PLOS
2009年5月26日 · Exon junction complexes (EJCs) link nuclear splicing to key features of mRNA function including mRNA stability, translation, and localization. We analyzed the formation of …
Exon Junction Complex (EJC) - SpringerLink
2016年1月1日 · The stable core complex of EJC includes four proteins (eIF4AIII [a DEAD-box protein], Barents [Btz]/MLN51 localization factor, Mago and Y14 [RNA localization factors]), …
One of the best-studied examples is the exon junction complex (EJC), a multiprotein complex deposited primarily 24 nucleotides upstream of exon–exon junctions as a consequence of pre …
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