GeneCards - Human Genes | Gene Database | Gene Search
2024年9月30日 · GeneCards is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and predicted human genes. The knowledgebase automatically integrates gene-centric data from ~200 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information.
Search - GeneCards
GeneCards is a comprehensive database that integrates various gene data sources, offering a search function for human gene information.
ACTG1 Gene - GeneCards | ACTG Protein | ACTG Antibody
2024年10月1日 · ACTG1 (Actin Gamma 1) is a Protein Coding gene. Diseases associated with ACTG1 include Deafness, Autosomal Dominant 20 and Baraitser-Winter Syndrome 2. Among its related pathways are Signaling downstream of RAS mutants and Regulation of actin dynamics for phagocytic cup formation.
CTNNB1 Gene - GeneCards | CTNB1 Protein | CTNB1 Antibody
2024年10月1日 · CTNNB1 (Catenin Beta 1) is a Protein Coding gene. Diseases associated with CTNNB1 include Pilomatrixoma and Colorectal Cancer. Among its related pathways are Signaling by CTNNB1 phospho-site mutants and Gastrulation. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and binding.
WAS Gene - GeneCards | WASP Protein | WASP Antibody
2024年10月2日 · WAS (WASP Actin Nucleation Promoting Factor) is a Protein Coding gene. Diseases associated with WAS include Wiskott-Aldrich Syndrome and Neutropenia, Severe Congenital, X-Linked. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Signaling by Rho GTPases.
VEGFA Gene - GeneCards | VEGFA Protein | VEGFA Antibody
2024年10月2日 · This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis.
TNF Gene - GeneCards | TNFA Protein | TNFA Antibody
2024年10月2日 · NCBI Gene Summary for TNF Gene. This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR.
BCL6 Gene - GeneCards | BCL6 Protein | BCL6 Antibody
2024年10月1日 · BCL6 (BCL6 Transcription Repressor) is a Protein Coding gene. Diseases associated with BCL6 include Intravascular Large B-Cell Lymphoma and High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit. Among its related pathways are Gene expression (Transcription) and Cytokine Signaling in Immune system.
PIK3CA Gene - GeneCards | PK3CA Protein | PK3CA Antibody
2024年10月2日 · PIK3CA (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha) is a Protein Coding gene. Diseases associated with PIK3CA include Megalencephaly-Capillary Malformation-Polymicrogyria Syndrome and Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi.
SERPINE1 Gene - GeneCards | PAI1 Protein | PAI1 Antibody
2024年10月2日 · This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity.