The many pathways of RNA degradation - PubMed
2009年2月20日 · RNA molecules with defects in processing, folding, or assembly with proteins are identified and rapidly degraded by the surveillance machinery. Because RNA degradation …
The Many Pathways of RNA Degradation - Cell Press
RNA molecules with defects in processing, folding, or assembly with proteins are identified and rapidly degraded by the surveillance machinery. Because RNA degradation is ubiquitous in all …
RNA Degradation - an overview | ScienceDirect Topics
RNA degradation is the process of targeting and breaking down RNA molecules to adjust transcript levels within cells. It involves using various compounds and mimics to degrade …
The highways and byways of mRNA decay - Nature
There are several surveillance mechanisms to degrade aberrant and unwanted mRNAs. These include nonsense-mediated decay, non-stop decay and no-go decay. Turnover of mRNAs is a …
A rapid inducible RNA decay system reveals fast mRNA …
2024年3月28日 · In this study, we established a rapid inducible RNA decay system by recruiting an RNA degradation factor on demand, and quantified RNA in subcellular compartments in …
RNA decay modulates gene expression and controls its …
They constitute a part of the Argonaute (AGO) RNA-induced silencing complex (RISC), a multiprotein complex that uses the guide RNA to recognize complementary target sites on …
Cytoplasmic RNA decay pathways - Enzymes and mechanisms
2016年12月1日 · Part One is dedicated to the key players governing RNA degradation in the cytoplasmic compartment and details the ways of mRNA decay initiation. Part Two presents …
RNA Degradation in Eukaryotic Cells | Molecular Biology
2020年8月19日 · The review considers the main RNA degradation enzymes, the decay pathways of various coding and non-coding RNAs, the mechanisms providing RNA quality control in the …
Unravelling the dynamics of RNA degradation by …
2006年9月7日 · We propose a reaction mechanism for exonucleolytic RNA degradation involving key conserved residues. Our three-dimensional model corroborates all existing biochemical …
5′ and 3′ modifications controlling RNA degradation: from …
2018年11月5日 · RNA degradation is a key process in the regulation of gene expression. In all organisms, RNA degradation participates in controlling coding and non-coding RNA levels in …