S-Nitrosylation - Wikipedia
In biochemistry, S-nitrosylation is the covalent attachment of a nitric oxide group (−NO) to a cysteine thiol within a protein to form an S-nitrosothiol (SNO). S-Nitrosylation has diverse …
S-Nitrosylation: An Emerging Paradigm of Redox Signaling
2019年9月17日 · S-nitrosylation is a selective covalent post-translational modification adding a nitrosyl group to the reactive thiol group of a cysteine to form S-nitrosothiol (SNO), which is a …
Protein S-Nitrosylation: Determinants of Specificity and …
Significance: Protein S-nitrosylation, the oxidative modification of cysteine by nitric oxide (NO) to form protein S-nitrosothiols (SNOs), mediates redox-based signaling that conveys, in large …
Protein S -nitrosylation: purview and parameters - Nature
2005年2月1日 · S-nitrosylation, the covalent attachment of a nitrogen monoxide group to the thiol side chain of cysteine, has emerged as an important mechanism for dynamic, post …
Biological Mechanisms of S-Nitrosothiol Formation and …
S-nitrosylation is as fundamental a form of posttranslational modification as phosphorylation. The likelihood of any cysteine thiol being modified is determined by the chemical reactivity of NO, …
Protein S-nitrosylation in health and disease: a current perspective
Protein S-nitrosylation conveys a large part of the ubiquitous influence of nitric oxide on cellular signal transduction, and accumulating evidence indicates important roles for S-nitrosylation …
The manifold roles of protein S-nitrosylation in the life of insulin
2021年11月17日 · Post-translational modification of insulin signalling proteins by S-nitrosylation is an under-appreciated, but widely used, control mechanism in health and disease. S …
S-Nitrosylation: NO-Related Redox Signaling to Protect Against ...
S -nitrosylation, the covalent attachment of an NO moiety to sulfhydryl residues of proteins, resulting in the formation of S -nitrosothiols (SNOs), is a prevalent posttranslational protein …
S-Nitrosylation in Tumor Microenvironment - PMC - National …
2021年4月27日 · S-nitrosylation is a selective and reversible post-translational modification of protein thiols by nitric oxide (NO), which is a bioactive signaling molecule, to exert a variety of …
S -nitrosylation of a receptor-like cytoplasmic kinase ... - Science
2024年3月15日 · Here we report that P/MAMP recognition leads to a rapid nitrosative burst, initiating the accumulation of nitric oxide (NO), subsequently leading to S-nitrosylation of the …