Spironolactone Online
Spironolactone is commonly used to treat conditions such as high blood pressure‚ heart failure‚ and hormonal acne. While it is a prescription-only medication‚ there are online platforms that offer telemedicine consultations to provide a prescription.
Spironolactone - StatPearls - NCBI Bookshelf
2023年7月4日 · Spironolactone is a medication used in the management and treatment of hypertension and heart failure with some indications aside from cardiovascular disease. It is in the mineralocorticoid receptor antagonist class of drugs.
Spironolactone: Uses, Interactions, Mechanism of Action
Spironolactone is indicated for the treatment of the following conditions: NYHA Class III-IV heart failure and reduced ejection fraction to increase survival, manage edema, and reduce the need for hospitalization for heart failure. Spironolactone is usually administered in conjunction with other heart failure therapies. 14
Spironolactone - Wikipedia
Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. [4]
Pharmacodynamics of spironolactone - Wikipedia
Spironolactone inhibits the effects of mineralocorticoids, namely, aldosterone, by displacing them from the mineralocorticoid receptor (MR) in the cortical collecting duct of kidney nephrons. This decreases the reabsorption of sodium and water while limiting the excretion of potassium.
ALDACTONE® Clinical Pharmacology - Pfizer Medical Information
By competing with aldosterone for receptor sites, spironolactone provides effective therapy for the edema and ascites in those conditions. Spironolactone counteracts secondary aldosteronism induced by the volume depletion and associated sodium loss caused by active diuretic therapy.
Spironolactone: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月17日 · Includes Spironolactone indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.
Spironolactone | Description, Mechanism of Action, Uses, & Side …
2024年11月23日 · Spironolactone is a diuretic drug that is used primarily to treat conditions related to edema (fluid retention), hypertension (high blood pressure), and hormone imbalances.
Spironolactone - DailyMed
Spironolactone counteracts secondary aldosteronism induced by the volume depletion and associated sodium loss caused by active diuretic therapy. Spironolactone is effective in lowering the systolic and diastolic blood pressure in patients with primary hyperaldosteronism.
Spironolactone - an overview | ScienceDirect Topics
Spironolactone is a potassium-sparing diuretic that binds to the distal tubule in the kidney as a binding competitor of aldosterone. Spironolactone slows the exchange of sodium and potassium in the distal tubule and has been approved for treating congestive heart failure and primary hyperaldosteronism.
Spironolactone - SpringerLink
2022年10月27日 · Spironolactone is a potassium-sparing diuretic with antiandrogenic effects since it decreases Testosterone levels, competitively blocks the cytosolic androgen receptor, reduces DHT effects in target tissues, and inhibits the mineralocorticoid receptor.
Spironolactone | C24H32O4S | CID 5833 - PubChem
Spironolactone is an aldosterone antagonist that acts on the mineralocorticoid receptor. It is a potassium-sparing diuretic, and hyperkalemia is the most common and potentially serious complication of therapy.
SPIRONOLACTONE- spironolactone tablet, film coated - DailyMed
Spironolactone tablets are aldosterone antagonist indicated for: The treatment of NYHA Class III-IV heart failure and reduced ejection fraction to increase survival, manage edema, and to reduce the need for hospitalization for heart failure ; Use as an add-on therapy for the treatment of hypertension, to lower blood pressure.
Spironolactone - PubMed
2023年7月4日 · Spironolactone is a medication used in the management and treatment of hypertension and heart failure with some indications aside from cardiovascular disease. It is in the mineralocorticoid receptor antagonist class of drugs.
Spironolactone is a competitive aldosterone antagonist with weak antiandrogenic effects, which inhibits the physiologic effects of aldosterone, including cellular hypertrophy, interstitial fibrosis and endothelial dysfunction, on the distal renal tubules, myocardium and vasculature.
Clinical management of patients with Cushing syndrome treated …
2020年10月29日 · Mifepristone is a competitive glucocorticoid receptor antagonist and progesterone receptor antagonist that is associated with several treatment effects and adverse events that clinicians need to be aware of when considering its use.
Drug-Induced Peripheral Neuropathy: A Narrative Review
This review synthesizes current clinical concepts regarding the mechanism, common inciting medications, and treatment options for drug-induced peripheral neuropathy.
Spironolactone | Treatment & Management | Point of Care
2023年7月4日 · Spironolactone is considered the main option for the treatment of ascites in cirrhosis after the dietary salt restriction is not sufficient. The typical starting dose ratio of oral furosemide to spironolactone is 40 mg to 100 mg, respectively.
Drug-Induced Peripheral Neuropathy: A Narrative Review - PMC
Drug-induced peripheral neuropathy is a common and painful condition caused by many different and frequently prescribed medications. Most often, DIPN is seen in chemotherapeutic agents, antimicrobials, cardiovascular drugs, psychotropic, and anticonvulsant drugs.
Mifepristone as Bridge or Adjunct Therapy in the Management of ...
2021年3月4日 · Mifepristone is a competitive glucocorticoid receptor antagonist that is approved in the US by the Food and Drug Administration to control hyperglycemia secondary to endogenous hypercortisolism (Cushing syndrome) in patients who have glucose intolerance or type 2 diabetes mellitus and have failed surgery or are not candidates for surgery.