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  1. SelfDecode Labs
    https://labs.selfdecode.com/blog/immunoglobulin-m

    IgM (Immunoglobulin M) Antibodies: Blood Test & Levels

    • Learn about IgM antibodies, the first-line defense of our immune system against infections. Find out what causes high or low IgM levels and how to improve your immune response.… 展开

    What Is Immunoglobulin M (Igm)?

    Antibodies are large proteins of the immune system that neutralize intruders, such as … 展开

    SelfDecode Labs
    Low Immunoglobulin M

    Low levels of IgM may mean your immune system is not working optimally. Because this antibody helps provide protection against bacteria and viruses, having low IgM levels has b… 展开

    SelfDecode Labs
    High Immunoglobulin M

    There are two types of IgM antibodies: natural and immune [1, 3]. The body produces immune IgM antibodies in response to intruders (antigens). That is why IgM levels t… 展开

    SelfDecode Labs
    Biochemistry, Immunoglobulin M - StatPearls - NCBI Bookshelf
    Introduction. IgM immunoglobulins are produced by plasma cells as part of the body's adaptive humoral immune response against a foreign pathogen. Resting mature yet naive, B lymphocyt…
    National Center for Biotechnology Information
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    目录
    What Is Immunoglobulin M (Igm)?
    Low Immunoglobulin M
    High Immunoglobulin M
     
  1. Largest of several isotypes of antibodies
    Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response to initial exposure to an antigen; causing it to also be called an acute phase antibody.

    Immunoglobulin M - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_M
    en.wikipedia.org/wiki/Immunoglobulin_M
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    What is immunoglobulin M (IgM)?
    Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response to initial exposure to an antigen; [ 1 ][ 2 ] causing it to also be called an acute phase antibody.

    Immunoglobulin M - Wikipedia

    en.wikipedia.org
    What are immunoglobulin M antibodies?
    Immunoglobulin M antibodies (IgM) are our first-line defense against a broad range of infections. They are often measured to help diagnose different conditions, such as infections, immunodeficiency, autoimmune disease, and certain types of cancer. Keep reading to learn more about high and low IgM levels and the factors that may affect them.

    IgM (Immunoglobulin M) Antibodies: Blood Test & Levels

    labs.selfdecode.com
    Is IGM a monomeric or transmembrane immunoglobulin?
    Antibodies are similar in structure to transmembrane immunoglobulins yet lack a short transmembrane segment at the carboxy-terminal end. IgM is the first antibody secreted by the adaptive immune system in response to a foreign antigen. Monomeric IgM is a heterotetramer of approximately 180 kDa.

    Biochemistry, Immunoglobulin M - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    Where are immunoglobulins located?
    Immunoglobulins are Y-shaped molecules containing 2 Fab regions that recognize antigens and an Fc tailpiece that determines the antibody's biological activity. In humans, the heavy chain locus is on chromosome 14, and 2 alternative light chain loci, known as kappa and lambda, are located on chromosomes 2 and 22, respectively.

    Biochemistry, Immunoglobulin M - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    Does immunoglobulin M improve disease symptoms in NZB X NZW mice?
    In the second study, treatment of NZB x NZW mice IgM anti-dsDNA improved disease symptoms including reduction in renal pathology and organ damage (137). Table 1 Role of immunoglobulin M (IgM) in infectious and non-infectious diseases.

    Frontiers | Immunoglobulin M in Health and Diseases: How Far Have We

    frontiersin.org
    What are IgM antibodies & why are they important?
    IgM (Immunoglobulin M) are the largest antibodies. They are the first-line defense of our immune system. They provide general but short-term protection against new infections. IgM levels decline as the body starts producing more IgG antibodies, which are responsible for long-term protection against pathogens [1, 2].

    IgM (Immunoglobulin M) Antibodies: Blood Test & Levels

    labs.selfdecode.com
    反馈
  3. WebMD
    https://www.webmd.com/a-to-z-guides/immunoglobulin-test

    Immunoglobulin Test: High vs Low vs Normal Levels of (Ig

  4. Wikipedia
    https://en.wikipedia.org/wiki/Immunoglobulin_M

    Immunoglobulin M - Wikipedia

  5. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK555995

    Biochemistry, Immunoglobulin M - StatPearls - NCBI …

    2022年12月19日 · Introduction. IgM immunoglobulins are produced by plasma cells as part of the body's adaptive humoral immune response against a foreign pathogen. Resting mature yet naive, B lymphocytes express IgM as a …

  6. 维基百科
    https://zh.wikipedia.org/wiki/免疫球蛋白M

    免疫球蛋白M - 维基百科，自由的百科全书

  8. 百度百科
    https://baike.baidu.com/item/免疫球蛋白M

    免疫球蛋白M - 百度百科

  9. Frontiers
    https://www.frontiersin.org/journals/imm…

    Frontiers | Immunoglobulin M in Health and Diseases: …

    2020年10月29日 · In this review, we explore how IgM structure and BCR signaling shapes B cell development, self and non-self-antigen-specific antibody responses, responses to infectious (such as viruses, parasites, and fungal) …

  10. MicrobiologyInfo.com
    https://microbiologyinfo.com/immunoglo…

    Immunoglobulin M (IgM) – Properties, Structure and …

    2024年1月23日 · Learn about the largest antibody, IgM, that is involved in primary immune responses, complement activation, and apoptotic cell clearance. Find out its structure, functions, and clinical significance in this …

  11. eMedicine
    https://emedicine.medscape.com/article/137693

    Immunoglobulin M Deficiency - Medscape

  12. Nature
    https://www.nature.com/articles/s41586-023-05835-w

    Immunoglobulin M perception by FcμR - Nature