Histone acetylation and deacetylation - Wikipedia
Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the nucleosome are acetylated and …
Acetylation of Histones and Transcription-Related Factors
Histones are by far the best-characterized acetylation substrates within chromatin, but most of the high-mobility-group (HMG) chromatin-associated proteins (reviewed in reference 33) are also …
Regulation of chromatin by histone modifications | Cell Research
2011年2月15日 · Histone acetylation and phosphorylation effectively reduce the positive charge of histones, and this has the potential to disrupt electrostatic interactions between...
Histone Acetylation - an overview | ScienceDirect Topics
Histone acetylation refers to a dynamic and reversible process in which histone tails are modified by the addition of an acetyl group. This modification is primarily regulated by histone …
Acetylation of histones and non-histone proteins is not a mere
2024年6月11日 · Here, we show that global protein acetylation remains virtually unaltered after acute transcription inhibition. Transcription inhibition ablates the co-transcriptionally occurring …
Histone acetylation and deacetylation – Mechanistic insights from ...
2024年1月10日 · Acetylation of histones is highly consequential to gene transcription. HATs and HDACs play critical roles in adding and erasing lysine acetylation. Recent cryoEM structures …
Histone acetylation: a switch between repressive and permissive ...
2002年3月3日 · Acetylation of histones H3 and H4 counteracts the tendency of nucleosomal fibers to fold into highly compact structures in vitro (Garcia-Ramirez et al., 1995; Tse et al., …
Modulation of cellular processes by histone and non-histone …
2022年1月18日 · Histone acetylation and non-histone protein acetylation influence a myriad of cellular and physiological processes, including transcription, phase separation, autophagy, …
Histone acetylation: influence on transcription, nucleosome …
1997年4月15日 · We demonstrate using a dinucleosome template that acetylation of the core histones enhances transcription by RNA polymerase III. This effect is not dependent on an …
Histone acylations and chromatin dynamics: concepts, …
2021年6月23日 · Acetylation of the ɛ‐amino group of lysines occurs on many lysines in histone tails and globular domains and is catalyzed by histone acetyltransferases (HAT). Acetylation …