What is the relationship between Digoxin and potassium?
2022年10月23日 · Digoxin works by two basic mechanisms of action and it is the mechanism at work in heart failure, involving inhibition of the Na+/K+-ATPase pump. The activity of the …
Cardiac glycoside poisoning (including digoxin) - EMCrit Project
2021年5月13日 · (1) Digoxin inhibits the cardiac Na/K antiporter (orange oval, above). This causes an increase in intracellular sodium and a decrease in intracellular potassium. The …
Digoxin: Pharmacology and toxicology—A review - ScienceDirect
2020年10月1日 · Digoxin exhibits its therapeutic and toxic effects by poisoning the Na + / K +-ATPase (Ren et al., 2020; Ambrosy et al., 2014). The subsequent increase in intracellular …
Digoxin and its Na+/K+-ATPase-targeted actions on …
2024年11月15日 · Digoxin targets Na + /K + -ATPase to mediate its bioactivities. Na + /K + -ATPase is a target for cardiovascular diseases and cancer. Digoxin has long been used …
Digoxin - StatPearls - NCBI Bookshelf
2023年1月19日 · Digoxin is a medication used to manage and treat heart failure, certain arrhythmias, and abortion. It is in the cardiac glycoside class of drugs. This article outlines the …
Risk of digoxin intoxication in heart failure patients exposed to ...
Increased frequency of electrolyte abnormalities and cardiac arrhythmias among patients exposed to digoxin–diuretic interactions has been well-documented in numerous descriptive studies. …
Digoxin and its Na+/K+-ATPase-targeted actions on …
Cardiac glycosides are well-known NKA inhibitors, of which (+)-digoxin or digoxin has been long used for the treatment of congestive heart failure. Also, digoxin has exhibited potential …
Oral digoxin effects on exercise performance, K
2022年8月8日 · We investigated whether digoxin lowered muscle Na +,K + ‐ATPase (NKA), impaired muscle performance and exacerbated exercise K + disturbances.
Digoxin - Cardiovascular - Medbullets Step 2/3
2021年12月17日 · He noticed that previously white objects now look yellow. He was recently started on digoxin. An echocardiogram reveals an atrioventricular block. He is found to be …
Myocardial Na,K-ATPase: the molecular basis for the …
2002年9月1日 · Thus, digoxin treatment is known to control symptoms of congestive heart failure when added to standard therapy. In this setting, we review the prevailing knowledge of the …