Opioids - Tramadol Megathread - Bluelight.org
1999年11月3日 · Tramadol is a fully synthetic opioid unlike opiates like Morphine or Codeine which are found in the poppy plant ( Papaverus Somniferum ) or semi-synthethic opioids like Diamorphine (Heroin) . Tramadol acts by binding to the μ-opioid receptor of the neuron and is also a serotonin–norepinephrine reuptake inhibitor.
Tramadol - Drugs-Forum
2011年10月6日 · Injection of crushed tramadol tablets is very dangerous. Injecting this form of tramadol whether IV, IM or subcutaneous risks overdose and death, and the fillers and binders in tramadol tablets when injected can cause local tissue necrosis, infection, pulmonary granulomas, and increased risk of endocarditis and valvular heart injury.
Injecting Can you inject Tramadol?? - Drugs-Forum
2009年6月14日 · Tramadol cannot metabolize the same efficacy when IV, equals loss of M1, most potent mu agonist product of tramadol. m1 is stronger than tramadol alone. Tramadol is best dosed 50mg every 5-10minutes for most m1 buildup. The process increases with efficiency when done this way. IV = less opioid, more SSRI/SNRI
Injecting - Tramadol pill and IV - Drugs-Forum
2006年7月21日 · Tramadol's have a delayed action. It takes around 4 hours before the real agonist (O-desmethyltramadol or the M1 metabolite) is created in the body by the liver. That is why the are not scheduled, because of this lack of feeling good in 15 minutes. Tramadol is a weak mu-agonist and it's M1 metabolite is 1000 times more active that tramadol.
can you inject tramadol IV? | Bluelight.org
2012年6月21日 · tramadol IVed isnt much different than taking it orally yeah the onset is faster, but it never gave me a rush the times I used it intravenously it was from a sterile vial meant for that purpose im not sure about the solubility of tramadol hcl pills in water, maybe someone will chime in with more scientific details
Opioids - IV tramadol questions - Bluelight.org
2007年9月21日 · Actually I had to go through a few days of Bupe withdrawal very recently; and I had only Tramadols. Shooting it (IV) gave an immediate relief (so Tramadol definitely does something even without being metabolized) (a stronger relief came after 2 hours though, so o-desmethyltramadol is still what gives most of the opiate-like effects of tramadols, but not all)
Opioids Tramadol Buzz - bluelight.org
2020年12月28日 · Tramadol is amazing man, but you cant take every dat, at the first i'm take 2 times per week, now i'm feel like a shit if dont take, its nice but, you need take the control., taking 500mg a day for 2 weeks and still feeling but, i cant stop now, really addiction.
Tramadol is available in various pharmaceuticalon multiple oral administration, possibly due to sat-forms. Ampoules contain 50mg (1mL) or 100mgurated first-pass hepatic metabolism.[12,23] The bio-(2mL) of tramadol in a solution for intravenous,availability of drops with ethanol is about the same intramuscular or subcutaneous injection.
Cold Water Extraction of Opioids - Drugs-Forum
2008年4月27日 · Codeine can be administered by many routes, this includes, SC, IM (intramuscularly), as an enema, and orally. Note: codeine can't be administered safely by IV (intravenously) injection as it can result in pulmonary edema (fluid in lungs), facial swelling and other life threatening complications. Codeine is converted to morphine in the brain.
Opioids - Tramadol recreational dose | Bluelight.org
2010年10月10日 · Hey all, I have some tramadol 50mg pills. I'm 65Kg / 143lbs and have zero tolerance to any opioids. 17 years old male.. only drug experience is with drinking and cannabis + ecstasy (once). Just wondering what would be a good dosage for a decent effect considering my background. Also, if...