Triazole - Wikipedia
A triazole is a heterocyclic compound featuring a five-membered ring of two carbon atoms and three nitrogen atoms with molecular formula C 2 H 3 N 3. Triazoles exhibit substantial …
1,2,3-Triazole - Wikipedia
1,2,3-Triazole is one of a pair of isomeric chemical compounds with molecular formula C 2 H 3 N 3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen …
A review on ‘triazoles’: their chemistry, synthesis and ... - Springer
Apr 22, 2021 · Triazoles are the five-membered heterocycles with three nitrogen atoms and two carbon atoms. There exist two tautomeric forms of triazole, i.e., 1, 2, 3-triazole and 1, 2, 4 …
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry
Oct 1, 2017 · Here, we provide an overview of the potential of triazole rings as bioisosteres, highlighting various examples and focusing our attention on 1,2,3-triazoles to stimulate and to …
Synthesis methods of 1,2,3-/1,2,4-triazoles: A review - PMC
Compounds containing a triazole are one of the significant heterocycles that exhibit broad biological activities, such as antimicrobial, analgesic, anti-inflammatory, anticonvulsant, …
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry
Moreover, the structural features of 1,2,3-triazole enable it to mimic different functional groups, justifying its wide use as a bioisostere for the synthesis of new active molecules. Here, we …
Application of triazoles as bioisosteres and linkers in the …
1,2,3-Triazole isomers are more common than 1,2,4-triazoles because of the ease of their synthesis and relatively better pharmacological properties. Different substitution patterns on …
1,2,3-Triazoles - PMC
The triazole ring in ruthenium complex 11, with average bond length of 1.353 Å, exhibits similar character to that of molecule 9 due in part to its resonance involving the carbonyl group at C-4. …
Frontiers | Triazoles and Their Derivatives: Chemistry, Synthesis, …
Apr 24, 2022 · The core triazole ring structures with higher aromatic stabilization energy are modified for improving solubility and selectivity with the interacting binding site of the enzyme …
Full article: Biological importance and synthesis of 1,2,3-triazole ...
Jan 30, 2024 · Triazole has the chemical formula C 2 H 3 N 3, consisting of a heterocyclic ring with three nitrogen atoms and two carbon atoms. Also known as pyrrodiazole, it occurs in two …